
Specialist information for medical staff
ON is your partner for innovative solutions in the field of weight reduction and nutritional optimization.
Our products are designed to support your patients on their journey to a healthier lifestyle. This page provides you with detailed information about our products and how to use them as part of a comprehensive weight management program.
Meal replacements are formulated to replace a full meal with all the necessary nutrients at a controlled calorie intake. They are an effective aid to weight loss and weight management as they facilitate the calorie deficit without sacrificing essential nutrients.
Benefits and application
ON meal replacements are designed to provide a balanced mix of macro and micronutrients to fully replace a meal. They are convenient for on-the-go and help to maintain a nutritional plan:
- Preset number of calories, which simplifies calorie counting
- Balanced composition of proteins, carbohydrates, fats, vitamins and minerals
- Contributes to satiety and reduces the feeling of hunger.

Instructions for specialist personnel
Physicians can use this information to offer patients who are overweight or obese a structured and nutritious option for weight loss. It is important to consider patients' individual needs and health conditions and use meal replacement products as part of a comprehensive treatment plan that includes nutritional counseling and physical activity.
Protein Meal Shake
ON's Protein Meal Shake offers an innovative and nutritious solution for weight loss and weight management. As part of our commitment to supporting a healthy lifestyle, the Protein Meal Shake has been specifically designed to replace a complete and balanced meal, with the aim of facilitating a calorie deficit without sacrificing essential nutrients.
The Protein Meal Shake offers a perfectly balanced combination of protein, fiber, vitamins and minerals, with only 205 calories per serving. It is enriched with ingredients such as:
- High-quality proteins: support muscle maintenance during weight reduction.
- Dietary fiber: Promotes a feeling of satiety and supports digestive health.
- 24 vitamins and minerals: ensure that your daily requirements are met and support your general health.
Thanks to this balanced composition, ON's Protein Meal Shake can help control hunger and make it easier to stick to a calorie-reduced diet plan.
Application recommendations
The Protein Meal Shake can replace two meals a day to support weight loss, or one meal a day to maintain weight. It is important that patients eat a balanced third meal in addition to the Protein Meal Shake to ensure they get all the nutrients they need.
Scientific basis
The development of the protein Meal Shake is based on current nutritional science and aims to support the achievement and maintenance of a healthy body weight. The composition has been chosen so that it can contribute to weight reduction as part of a calorie-controlled diet plan.
For medical professionals
We encourage physicians to recommend ON's Protein Meal Shake as part of a comprehensive weight management program that includes nutritional counseling and physical activity. For more information or to discuss specific patient cases, please contact our medical team at aerzte-support@offset-nutrition.com.

The recommendation of meal replacement products such as ON Meal Replacement (MZE) and ON Weight Loss Plan by physicians to their patients is based on a combination of scientific research, practical versatility and patient-centered benefits. These products can be an effective complement to traditional weight loss methods, including the use of weight loss injections.
Technical reasons for use
Proven effectiveness
Studies show that meal replacements are an effective method for weight loss and management, providing nutrients and making it easier to stick to diet plans (Heymsfield et al., 2018).
Complementary application with slimming syringes
Weight loss injections for hunger control can be effectively supplemented with ON MZE to control calories and provide nutritious support for the calorie deficit.
Diversity and flexibility
ON offers meal replacements in over 40 varieties, e.g. shakes, bars, muesli and pancakes. The variety prevents nutritional monotony, takes individual preferences into account and supports long-term motivation for weight reduction plans.
Simplicity & suitability for everyday use
The ON MZE Shake is simply prepared with milk and requires no oil, providing a quick, healthy and filling meal and making it easier to stick to your weight loss plan.
Further information
Heymsfield, S. B., van Mierlo, C. A., van der Knaap, H. C., Heo, M., & Frier, H. I. (2003). Weight management using a meal replacement strategy: meta and pooling analysis from six studies. International Journal of Obesity, 27(5), 537-549. This meta-analysis shows that the use of meal replacement products can lead to significant weight loss.
LeCheminant, J. D., & Gibson, C. A. (2005). Effect of exercise and physical activity on weight loss and maintenance. Progress in Cardiovascular Diseases, 47(6), 396-412. This review emphasizes the importance of physical activity as an adjunct to dietary interventions such as meal replacement for effective weight management.
By recommending the OFFSET Nutrition meal replacement and accompanying weight loss plan to their patients, physicians offer a science-based, convenient and flexible option to support their weight loss goals. The combination with weight loss injections and the variety of products increase the likelihood that patients will stay motivated and achieve long-term success.
According to EFSA guidelines, the following health claims can be made in relation to meal replacement products for weight reduction and control:
Weight loss:
"Replacing two of the daily meals as part of a low-calorie diet with meal replacements contributes to weight loss." This supports the use of meal replacements as part of a structured diet program to achieve a calorie deficit.
Weight maintenance after weight loss
"Replacing one of the daily meals as part of a low-calorie diet with a meal replacement helps to maintain weight after weight loss." This claim emphasizes the role of meal replacement products in long-term weight control after an initial weight loss phase.
The development of the Protein Meal Shake is based on current nutritional science and aims to support the achievement and maintenance of a healthy body weight. The composition has been chosen so that it can contribute to weight reduction as part of a calorie-controlled diet plan.
studies show that meal replacements, when used as part of a calorie-controlled diet plan, can effectively contribute to weight reduction. The structured approach makes it easier to stick to the diet and thus promotes long-term weight management success.
Studies have shown that meal replacements can be an effective strategy for weight loss and weight management. They provide a controlled calorie intake, are rich in essential nutrients and support adherence to diet plans. The systematic review and meta-analysis by Heymsfield et al. (2018) suggests that meal replacements, especially when integrated into a structured diet plan, can significantly contribute to weight loss compared to traditional dieting methods.
Frequently asked questions
ON Meal Replacement is designed to replace one or two main meals a day to support weight loss or weight management. It is rich in essential nutrients and helps to achieve a calorie deficit without sacrificing a balanced nutritional intake. However, it is important that patients also eat a balanced third meal to ensure a complete and healthy diet.
The ON meal replacement can be an effective supplement to weight loss injections by providing a nutrient-rich meal option with a controlled calorie count. This helps to support the calorie deficit induced by weight loss injections, while ensuring that the body receives all the nutrients it needs.
The variety in shapes and flavors of ON Meal Replacement aims to prevent monotony in the diet and promote adherence to the weight loss plan. By providing over 40 attractive varieties and delivery forms, such as shakes, bars, cereals and pancakes, individual taste preferences and lifestyles can be catered for.
The ON Shake is simply prepared by mixing with milk without adding oil. This makes it a quick, convenient and healthy meal option that can be easily integrated into everyday life. The ease of preparation encourages adherence to the diet plan and supports long-term commitment to weight management.
ON meal replacement products are suitable for most people looking for a convenient solution for weight loss and management. However, it is recommended that individuals with special dietary needs or health conditions seek advice from a healthcare professional before use.
Yes, the ON meal replacement was developed with the needs of diabetics in mind. This means that special emphasis has been placed in the formulation on a low glycemic index (GI) and the control of sugar levels to avoid blood sugar spikes. Products with a low GI release glucose into the bloodstream more slowly, which allows for more stable blood sugar control and is therefore beneficial for diabetics.
In addition, ON's meal replacement products contain a balanced blend of macro and micronutrients specifically designed to support the nutritional needs of diabetics without negatively impacting their blood sugar levels. This makes ON meal replacements a safe and potent option for diabetics looking for effective weight management and weight loss solutions, provided they are used as part of a comprehensive and physician-supervised diet plan.
However, it is important that diabetics always make individual dietary recommendations and adjustments in consultation with their treating physician or a dietitian to ensure that meal replacements are optimally integrated into their specific health plan

Contact for queries
For further information or specific requests, we offer a dedicated e-mail address: aerzte-support@offset-nutrition.com
Our team of experts will be happy to answer your questions and help you get the most out of our products.














